Alexander (better known as “Sasha”) and Ann Shulgin’s foundational work in the genre was the first book to fully impart the how-to chemistry, and convey the effects, of many of the entheogenic drugs that are currently being studied and used to heal trauma and deal with death. An acronym for “Phenethylamines I Have Known and Loved”, the book spans autobiography, organic chemistry, politics, ethnobotany, and psychopharmacology, and the cultural impact is likely to be profound for decades to come, as it has already. PiHKAL is divided into two parts, the first of which is a fictionalized autobiographical 'novel' - the main fiction is that it is fiction. This first half of the book is The Love Story, about two people named Shura and Alice who fall in love, though one of them is already in love with someone else. This love triangle is a painful ordeal they must go through, and that process unfolds before the reader with grace and great insight into human nature. Shura is a brilliant chemist who has dedicated his career to making psychoactive drugs, in the story they go through many experiences with the psychedelic compounds that Shura has discovered and has made in his lab, all of which have been bioassayed himself. The reader will find themselves going on this journey with them, experiencing what they experienced, both in their hearts and in the psychedelic journeys they have. The second half of PiHKAL is called The Chemical Story, and it contains detailed instructions for, and effects of, the synthesis of 179 psychedelic phenethylamines, which were mostly discovered by Shulgin himself. For each substance there is information on its synthesis, suggested effective dosage, duration, and detailed commentary on the subjective effects that were experienced. This book appeals to adults of all ages and cultures, and to the psychedelically experienced and inexperienced alike. Read more

Alexander (better known as “Sasha”) and Ann Shulgin’s PiHKAL: A Chemical Love Story has become a foundational work in the genre and was the first book to fully impart the how-to chemistry, and convey the effects, of many of the entheogenic drugs that are currently being studied and used to heal trauma and deal with death. An acronym for “Phenethylamines I Have Known and Loved”, the book spans autobiography, organic chemistry, politics, ethnobotany, and psychopharmacology, and the cultural impact is likely to be profound for decades to come, as it has already. PiHKAL is divided into two parts, the first of which is a fictionalized autobiographical "novel" - the main fiction is that it is fiction. This first half of the book is The Love Story, about two people named Shura and Alice who fall in love, though one of them is already in love with someone else. This love triangle is a painful ordeal they must go through, and that process unfolds before the listener with grace and great insight into human nature. Shura is a brilliant chemist who has dedicated his career to making psychoactive drugs. In the story, they go through many experiences with the psychedelic compounds that Shura has discovered and has made in his lab, all of which have been bioassayed himself. The listener will find themselves going on this journey with them, experiencing what they experienced, both in their hearts and in the psychedelic journeys they have. The second half of PiHKAL is called The Chemical Story, and it contains detailed instructions for, and effects of, the synthesis of 179 psychedelic phenethylamines which were mostly discovered by Shulgin himself. For each substance there is information on its synthesis, suggested effective dosage, duration, and detailed commentary on the subjective effects that were experienced. This book appeals to adults of all ages and cultures, and to the psychedelically experienced and inexperienced alike. Read more

An evolutionary biologist tells the story of nature’s toxins and why we are attracted—and addicted—to them, in this “magisterial, fascinating, and gripping tour de force” (Neil Shubin).A deadly secret lurks within our spice racks, medicine cabinets, backyard gardens, and private stashes.Scratch beneath the surface of a coffee bean, a red pepper flake, a poppy seed, a mold spore, a foxglove leaf, a magic-mushroom cap, a marijuana bud, or an apple seed, and we find a bevy of strange chemicals. We use these to greet our days (caffeine), titillate our tongues (capsaicin), recover from surgery (opioids), cure infections (penicillin), mend our hearts (digoxin), bend our minds (psilocybin), calm our nerves (CBD), and even kill our enemies (cyanide). But why do plants and fungi produce such chemicals? And how did we come to use and abuse some of them?Based on cutting-edge science in the fields of evolution, chemistry, and neuroscience, Most Delicious Poison reveals:The origins of toxins produced by plants, mushrooms, microbes, and even some animalsThe mechanisms that animals evolved to overcome themHow a co-evolutionary arms race made its way into the human experienceAnd much moreThis perpetual chemical war not only drove the diversification of life on Earth, but also is intimately tied to our own successes and failures. You will never look at a houseplant, mushroom, fruit, vegetable, or even the past five hundred years of human history the same way again. Read more

• A micro-encyclopedia for those who want to know the perfumer's work and learn about the perfume industry from the inside, but have no guide on where to start. Read more

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Dive into the transformative world of chemical reactions with "Catalysts at Work," a comprehensive journey through the art and science of catalysis poised to become an essential read for those passionate about engineering marvels at the molecular level.In this enthralling e-tome, unfold the enigma of catalysis—a phenomenon central to modern-day manufacturing, environmental protection, and energy solutions. From the comfort of your digital device, embark on a spectacular voyage from the roots of catalytic science to the frontiers leading us into a sustainable future."Catalysts at Work" initiates the expedition with a detailed exploration of the fundamentals—grasping underlying principles that compose the cornerstone of chemical engineering. Witness the historical evolution of catalysts, delve into the fascinating dichotomy of homogeneous and heterogeneous catalysis, and captivate your intellect with the intricate surface science driving catalytic reactions.Transition from the basics to an in-depth analysis of catalyst composition, engage with the nuances of their interactions, and investigate the regenerative strategies vital for their longevity. The text navigates you through an arsenal of characterization techniques, revealing the groundbreaking spectroscopic and microscopic methods that lay bare the secrets of catalyst behavior.Prepare to synthesize knowledge and application as you step into a realm where kinetics and reaction mechanisms elucidate the choreography of atoms in orchestrated chemical ballets. Expand your horizon into the innovative domain of catalytic material design, where nanotechnology and bio-inspiration converge to revolutionize catalyst synthesis and application.Through subsequent chapters, immerse yourself in a world where the environment reigns supreme. Embrace the green chemistry ideals and discover how catalysts can mitigate pollution while fostering sustainability in the automotive industry and beyond.From the granular scale of laboratories to the colossal sweep of industrial plants, "Catalysts at Work" connects theory with real-world praxis, offering glimpses into the sophisticated operation of petrochemical refining and the finesse of polymerization catalysis. Challenge your intellect with the optimization processes that scale the very pinnacles of research to tangible, market-ready solutions.Approach the horizon with an insightful forecast into the future of catalysis, evaluating challenges, embracing emerging technologies, and designing the blueprints for a circular economy. Revel in detailed case studies that showcase catalytic reaction engineering, and navigate the ethical landscape of research with safety and intellectual property at the helm.Join us on this enthralling quest through "Catalysts at Work," destined to elevate your understanding and ignite a spark that will fuel innovation, dedication, and reverence for the science and application of catalysts. Whether you're a scholar, an enthusiast, or a professional in the field, this book will lead you through an enlightening odyssey where every chapter unveils vital components shaping the world we inhabit and hope to sustain for generations to come. Read more

Discover the hidden secrets of poisons and toxins with Toxicology Unveiled, a comprehensive guide that takes you through the multifaceted world of toxic substances. Dive deep into a subject that intertwines science, history, and detective work to uncover the mysteries of poisons and their impact on our lives.Start your journey with an insightful introduction to toxicology, exploring the captivating history of poisons and the essential roles of toxicologists. Transition into the basic principles of drug detection, understanding mechanisms of drug action, and the processes of absorption, distribution, and metabolism. Grasp the interplay of pharmacokinetics and pharmacodynamics in toxicology.Unveil the diverse world of toxic substances with detailed classifications, covering naturally occurring toxins to synthetic ones. Master advanced analytical techniques like chromatography, mass spectrometry, and spectrophotometry for precise poison detection.Explore the gripping field of forensic toxicology with real-life case studies and learn the intricate techniques used in postmortem examinations. Delve into clinical toxicology, focusing on diagnosis, treatment, and the invaluable role of clinical labs.Understand the environmental effects of toxicants, the impact on wildlife, and the phenomena of bioaccumulation and biomagnification. Investigate occupational toxicology and learn about safety measures and notable workplace poisoning incidents.Examine food and drug toxicology, from contaminants in our food supply to the rigorous safety testing of pharmaceuticals. Navigate the cutting-edge advancements in toxicogenomics, emphasizing genetic susceptibility and personalized medicine.Uncover the lifesaving world of poison antidotes, their mechanisms, and emerging treatments. Stay ahead with the latest techniques for detecting drugs and poisons, including innovative immunoassays, biosensors, and lab-on-a-chip technology.Relish fascinating case studies, from historical poisoning events to modern overdoses and unsolved toxicology mysteries. Look ahead to the future of toxicology with emerging detection methods, the integration of artificial intelligence, and the rise of new poisons and drugs. Finally, ponder the ethical and legal dilemmas that shape the field today.Toxicology Unveiled is your ultimate guide to a world where science meets mystery, offering an enlightening perspective on the substances that can heal or harm us. Prepare to be captivated and informed by the intriguing realm of toxicology. Read more

TiHKAL: The Continuation is the sequel to PiHKAL: A Chemical Love Story but can stand alone to any reader. Where PiHKAL focuses on a class of compounds called phenethylamines, TiHKAL is written about a family of psychoactive drugs known as tryptamines with TiHKAL being an acronym for "Tryptamines I Have Known and Loved”. Like its predecessor PiHKAL, it is divided into two parts. The first part of the book begins with the story of Alice and Shura, a fictionalized autobiography, which picks up where the similar section of PiHKAL left off. The book opens with the story about the DEA raid that occurred a few years after the publication of their first book, PiHKAL. It’s a window into the DEA, the institutional aspect and human side of it as well, and the price that Shura and Alice pay for doing what they do, including exercising their first amendment rights. It then continues with a collection of essays on topics ranging from psychotherapy and the Jungian mind, to the prevalence of DMT in nature, ayahuasca, the War on Drugs, and even the Big Bang. It is a blend of travel, botanical facts, scientific speculation, psychological and political commentary. It is fascinating getting to know the mind of the man behind the compounds - his thoughts on science, technology, law, and society. And the mind of the woman who brought his work and their story into the light of the world. The second part of TiHKAL is “The Chemistry Continues”. It is a detailed manual for 55 psychedelic compounds (many discovered by Shulgin himself). For each compound there is information on synthesis, effective dosage, duration of effects, and commentary on the subjective effects that were experienced. The Shulgins' two big books span autobiography, organic chemistry, politics, ethnobotany and psychopharmacology and the cultural impact of these works has been profound and will continue to be so in the future. Read more

A world-renowned authority on the science of alcohol exposes its influence on our health, mood, sleep, emotions, and productivity - and what we can and should do to moderate our intake. From after-work happy hour to a nightly glass of wine, we're used to thinking of alcohol as a normal part of our daily lives. In Drink?, neuropharmacology professor David Nutt takes a fascinating, science-based look at drinking to unpack why we should reconsider our favorite pastime. Using cutting-edge scientific research and years of hands-on experience in the field, Nutt delves into the long- and short-term effects of alcohol. He addresses topics such as hormones, mental health, fertility, and addiction, explaining how alcohol travels through our bodies and brains, what happens at each stage of inebriation, and how it effects us even after it leaves our systems. With accessible, easy-to-understand language, Nutt ensures that listeners recognize why alcohol can have such a negative influence on our bodies and our society. In the vein of This Naked Mind, Drink? isn't preachy; it simply gives listeners clear, evidence-based facts to help them make the most informed choices about their consumption. PLEASE NOTE: When you purchase this title, the accompanying PDF will be available in your Audible Library along with the audio. Read more

Millions of people are suffering from chronic illnesses that, unbeknownst to them, are the result of exposure to environmental toxins and infectious agents such as mold and Borrelia, which causes Lyme disease. Millions. Because the symptoms of these illnesses are so varied and unusual, many of these individuals have sought medical care only to be dismissed, as if what they are experiencing is “in their head.” Many (if not most) have tried to tough it out and continue to function without hope of improvement. Unfortunately, their illnesses are very real. Toxic is a book of hope for these individuals, their loved ones, and the physicians who provide their care. Over many years of helping thousands of patients recover their health (even after their previous doctors had given up on them), Dr. Neil Nathan has come to understand some of the most common causes for these debilitating illnesses, which allows for the utilization of more precise and effective forms of treatment. The goal of this book is to shed light on these complex illnesses so that suffering patients and their families can get the help they so desperately need. Inside, you will find: • Information about how extreme sensitivity and toxicity develop in the body, how sensitivity and toxicity differ, and how they often overlap• Detailed descriptions of each of the five major causes of extreme sensitivity and toxicity: mold, Bartonella (a co-infection of Lyme disease), mast cell activation, porphyria, and carbon monoxide poisoning• An outline of the cell danger response, a revolutionary model developed by Dr. Robert Naviaux that explains how the body essentially gets “stuck” fighting a threat even after the danger has passed• A system-by-system plan for “rebooting” the body to break the cycle of illness and allow healing to begin• Information about coping with stress and embracing an emotional and/or spiritual awakening on the path to wellness Read more

Modern perfumery is a blend of art, science and technology, with chemistry being the central science involved. The Chemistry of Fragrances aims to educate and entertain, and inform the audience of the very latest chemistry, techniques and tools applied to fragrance creativity. Beginning with the history of perfumes, which goes back over fifty thousand years, the book goes on to discuss the structure of the Perfume Industry today. The focus then turns to an imaginary brief to create a perfume, and the response to it, including that of the chemist and the creative perfumer. Consumer research, toxicological concerns, and the use of the electronic nose are some of the topics discussed on this journey of discovery. Written by respected experts in their fields, this unique book gives an insider view of ""mixing molecules"" from behind the portals of modern-day alchemy. It will be enjoyed by chemists and marketeers at all levels. Read more

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Chemical Process An Introduction to Theory and Practice by George Stephanopoulos. Read more

An evolutionary biologist tells the story of nature’s toxins and why we are attracted—and addicted—to them, in this “magisterial, fascinating, and gripping tour de force” (Neil Shubin). A deadly secret lurks within our spice racks, medicine cabinets, backyard gardens, and private stashes. Scratch beneath the surface of a coffee bean, a red pepper flake, a poppy seed, a mold spore, a foxglove leaf, a magic-mushroom cap, a marijuana bud, or an apple seed, and we find a bevy of strange chemicals. We use these to greet our days (caffeine), titillate our tongues (capsaicin), recover from surgery (opioids), cure infections (penicillin), mend our hearts (digoxin), bend our minds (psilocybin), calm our nerves (CBD), and even kill our enemies (cyanide). But why do plants and fungi produce such chemicals? And how did we come to use and abuse some of them? Based on cutting-edge science in the fields of evolution, chemistry, and neuroscience, Most Delicious Poison reveals: The origins of toxins produced by plants, mushrooms, microbes, and even some animals The mechanisms that animals evolved to overcome them How a co-evolutionary arms race made its way into the human experience And much more This perpetual chemical war not only drove the diversification of life on Earth, but also is intimately tied to our own successes and failures. You will never look at a houseplant, mushroom, fruit, vegetable, or even the past five hundred years of human history the same way again. Read more

Named a “Best Book of the Year” by Kirkus Reviews“Urgent and eye-opening, the book serves as a loud-and-clear alarm.”―The Boston GlobeNamed an "Outstanding Academic Title" by Choice From an MIT scientist, mounting evidence that the active ingredient in the world’s most commonly used weedkiller is contributing to skyrocketing rates of chronic disease.Glyphosate is the active ingredient in Roundup, the most commonly used weedkiller in the world. Over 300 million pounds of glyphosate-based herbicide are sprayed on farms―and food―every year.Agrochemical companies claim that glyphosate is safe for humans, animals, and the environment. But emerging scientific research on glyphosate’s deadly disruption of the gut microbiome, its crippling effect on protein synthesis, and its impact on the body’s ability to use and transport sulfur―not to mention several landmark legal cases―tells a very different story.In Toxic Legacy, senior research scientist Stephanie Seneff, PhD, delivers compelling evidence based on countless published, peer-reviewed studies―all in frank, illuminating, and always accessible language.As Rachel Carson did with DDT in the 1960’s with Silent Spring, Seneff sounds the alarm on glyphosate, giving you guidance on simple changes you can make right now and essential information you need to protect your health, your family’s health, and the planet on which we all depend.“A game-changer that we would be foolish to ignore.”―Kirkus Reviews (starred)“Toxic Legacy will stand shoulder to shoulder with Rachel Carson’s Silent Spring. [This is] unquestionably, one of the most important books of our time.”―David Perlmutter, MD, #1 New York Times bestselling author of Grain Brain“Dr. Seneff’s work will change the way we all think about food.”―Mark Hyman, MD, New York Times bestselling author Read more

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Renowned perfumer Mandy Aftel explores the primal nature and fundamental importance of aroma in everyday life, teaching people about the nature of smell and the idea of "olfactory consciousness" in Essence and Alchemy: A Natural History of Perfume. Read more

Essential reading on segregation.In June 1892, a thirty-year-old shoemaker named Homer Plessy bought a first-class railway ticket from his native New Orleans to Covington, north of Lake Pontchartrain. The two-hour trip had hardly begun when Plessy was arrested and removed from the train. Though Homer Plessy was born a free man of color and enjoyed relative equality while growing up in Reconstruction-era New Orleans, by 1890 he could no longer ride in the same carriage with white passengers. Plessy's act of civil disobedience was designed to test the constitutionality of the Separate Car Act, one of the many Jim Crow laws that threatened the freedoms gained by blacks after the Civil War. This largely forgotten case mandated separate-but-equal treatment and established segregation as the law of the land. It would be fifty-eight years before this ruling was reversed by Brown v. Board of Education. Keith Weldon Medley brings to life the players in this landmark trial, from the crusading black columnist Rodolphe Desdunes and the other members of the Comité des Citoyens to Albion W. Tourgee, the outspoken writer who represented Plessy, to John Ferguson, a reformist carpetbagger who nonetheless felt that he had to judge Plessy guilty. Read more

The second edition defines the tools used in QA/QC, especially the application of statistical tools during analytical data treatment. Clearly written and logically organized, it takes a generic approach applicable to any field of analysis. The authors begin with the theory behind quality control systems, then detail validation parameter measurements, the use of statistical tests, counting the margin of error, uncertainty estimation, traceability, reference materials, proficiency tests, and method validation. New chapters cover internal quality control and equivalence method, changes in the regulatory environment are reflected throughout, and many new examples have been added to the second edition. Read more

World acclaimed scientist Vaclav Smil reveals everything there is to know about nature's most sought-after resourceOil is the lifeblood of the modern world. Without it, there would be no planes, no plastic, no exotic produce, and a global political landscape few would recognise. Humanity’s dependence upon oil looks set to continue for decades to come, but what is it? Fully updated and packed with fascinating facts to fuel dinner party debate, Professor Vaclav Smil's Oil: A Beginner's Guide explains all matters related to the ‘black stuff’, from its discovery in the earth right through to the controversy that surrounds it today. Read more